TL;DR:

• Omega-3s help build healthy cells, hormones, and brain tissue for both mother and baby.
• Studies show omega-3 supplements in late pregnancy may lower risks of wheeze, asthma, and egg or peanut allergies in children.
• Results for eczema are mixed—a balanced diet and probiotics may help further.

Essential Fatty Acids Matter

The fats and oils in your diet have far-reaching consequences for your health. Fats are what your body uses to create the cell membrane and to create hormones, just to name a couple of uses. Eating fried foods and processed oils can create health problems. By the same token, taking essential fatty acids usually provides health benefits.

Omega-3 Oils Are Well-Studied

Omega-3 fatty acids from fish oil have been extensively studied because most Americans don’t get them in their diets. One study looked at prenatal care for the mothers of 706 infants at high hereditary risk of developing allergies. In the randomized, placebo-controlled study, mothers were either given a placebo or 900 mg of omega-3 fatty acids per day from the 21st week of gestation until birth. There was an overall reduced prevalence of egg sensitivity and atopic eczema in the group receiving the fish oil. There was a slight decrease in immunoglobulin E associated allergic disease (13% in the control group, compared to 9% in the group receiving the omega 3 oil) [1].

Since the 2012 BMJ trial, larger studies and meta-analyses suggest that maternal omega-3 intake during late pregnancy can lower the risk of some allergic outcomes in children—most consistently persistent wheeze/asthma [2], and in several analyses egg or peanut sensitization [3]—while effects on eczema are mixed overall (probiotics may help here, click to learn more).

Simply taking omega-3 fatty acids is an extremely limited strategy for preventing childhood allergies. They can, of course, be an important part of your overall dietary plan. You are building a human being and the old tech cliché “GIGO” (garbage in, garbage out) applies. Eat nutrient-dense foods and avoid ultra processed foods [4,5].

FAQs

Q: Do omega-3 supplements during pregnancy reduce allergies?
A: Studies show fewer cases of wheeze/asthma and egg or peanut sensitization in children when mothers take omega-3s in late pregnancy.

Q: How much omega-3 should a pregnant woman take?
A: Clinical trials use 900 mg–2.4 g per day of combined EPA and DHA starting around 20–24 weeks gestation.

Q: Can omega-3s prevent eczema?
A: Results are mixed; probiotics and a diverse maternal diet may further support skin health.

  1. British Medical Journal (2012;344:e184 (Published 31 January 2012)) Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants’ allergies in first year of life: randomised controlled trial
  2. December 29, 2016 N Engl J Med 2016;375:2530-2539 Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring
  3. J Allergy Clin Immunol Pract. 2023 Sep;11(9):2862-2871.e8. Maternal Omega-3 Supplementation During Pregnancy, but Not Childhood Supplementation, Reduces the Risk of Food Allergy Diseases in Offspring
  4. BMJ Nutrition, Prevention, and Health 7 December 2023 Maternal diet and complementary food diversity on allergy prevention
  5. 2024 Apr 8;16(7):1087. Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention